Lin4Neuro is based on Ubuntu (16.04LTS or 14.04LTS), so the system requirement is the same as Ubuntu. However, you need much more powerful CPU and memory to run neuroimaging software packages included in Lin4Neuro. System requirements for Freesurfer might be useful:
- A 2GHz or faster processor
- At least 4GB of RAM
- 3D graphics card (with a GPU and its own graphics memory) with accelerated OpenGL drivers
- 17″ or bigger monitor
As of HDD, if you would like to boot from USB flash drive, you need to prepare USB-HDD. (If you install MS-Windows on your PC, I recommend not to use internal HDD to save the data, because it may cause some problems.)
In addition to the requirement above, please check if your system can be booted from USB.